Post-doctorate in ecophysiology
14 months from June 1, 2022 (start date can be negotiated) Location: UMR 5023, University of Lyon 1, Lyon (France) Type of contract: Fixed-term contract
The University Claude Bernard - Lyon 1, is a major research institution in Europe with an annual budget of more than 420 million euros, approximately 2,800 teaching researchers and more than 48,000 students. Within the UMR 5023 (Laboratory of Ecology of Natural and Anthropised Hydrosystems), the Ecophysiology, Behaviour, Conservation team (https://umr5023.univ- lyon1.fr/equipes-de-recherche/e2c ) studies the impact of environmental modifications (natural and anthropic) on the ecology, behaviour and physiology of organisms.
For several years, we have been developing a research programme on the impact of light pollution on amphibians. We have shown that artificial light at night alters the activity and metabolism of amphibians as well as their reproductive behaviour and egg fertilisation capacity. At the molecular level, the gene expression pattern is strongly modified by night light in tadpoles. These transcriptomic analyses suggest that immune function may be particularly affected by light pollution.
We are now looking for a post-doc to develop this project to determine which immune pathways are impacted by light pollution and whether the under-expression of many immune-related genes results in immuno-depression in the animals. The successful candidate will participate in the conception and execution of experiments on amphibian species (target gene, physiological and in-organism approaches), phenotypic analyses and genomic transcriptomic data and lead the writing of the resulting manuscript(s). In addition to knowledge of immunity, the successful candidate should have a strong background in ecology and experimental approaches, as well as in data analysis (good knowledge of R). In order to assess whether there is a common pattern of immunity response to light pollution, the postdoc may also collaborate with UMR 5558 with an insect study model.
Recommended training: PhD in Ecophysiology / Biology / Ecology
Desired knowledge: Knowledge of immune physiology, conservation biology, genetic data analysis
Experience: Molecular biology and bioinformatics, animal experimentation (French level 2 or equivalent)
English spoken and written
Autonomous in terms of organisation, ability to work in multidisciplinary projects
Please attach a CV, a covering letter and the contact details of two referees.
Touzot M., Teulier L., Lengagne T., Secondi J., Théry M., Libourel P.A., Guillard L., Mondy N. 2019. Artificial light at night disturbs the activity and energy allocation of the common toad during the breeding period. Conservation Physiology, 7: 1-9.
Touzot, M., Lengagne, T., Secondi, J., Desouhant, E., Théry, M., Dumet, A., Duchamp, C., Mondy, N., 2020 - Artificial light at night alters the sexual behaviour and fertilisation success of the common toad. Environmental Pollution, 259, 113883.
Secondi J., Mondy N., Gippet J., Touzot M., Gardette V., Guillard L., Lengagne T. 2021. Artificial light at night alters activity, body mass and corticosterone level in a tropical anuran. Behavioral Ecology, 32, 5: 932-940.
Touzot M., Lefebure T., Lengagne T., Secondi J., Dumet A., Konecny-Dupre L., Veber P., Navratil V., Duchamp C., Mondy N. 2022. Large scale deregulation of gene expression by a artificial light at night in tadpoles of common toads. Science of The Total Environment, 818, 151734